STD DONOVANOSIS: TREATMENT

This bacterial infection is treated with antibiotics. In the United States, the first choices are doxycycline or trimethoprim-sulfamethoxazole. Ciprofloxacin and erythromycin are second choices.

Although treatment is only successful if it is continued until the infection has been cleared—usually in about three weeks—and the infection may recur if the antibiotics are stopped sooner, it is sometimes difficult for various reasons for people to take the full course of antibiotics. Studies are under way to determine whether medications such as azithromycin, which remain in the body longer (and thus require fewer doses to be taken), are a reasonable alternative.

Scarring may persist despite adequate treatment, but it is usually minimal if medical attention is sought early in the infection. If a secondary bacterial infection develops on top of the donovanosis, it may need to be treated with different antibiotics.

Treatment may not be as successful in a person who has a compromised immune system, such as one with HIV infection. In this case, the medications are taken for a longer period.

All sexual partners of a person with donovanosis for a period of up to sixty days before the infected person developed symptoms must be treated with antibiotics, even if they are symptom free.

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